3-in-1 Combination Formula

Hims Review 2026: Hims 3-in-1

The only combination ED formula with oxytocin — targeting the relational and emotional dimension of intimacy alongside physical function.

Onset: 30–60 minutes Duration: Up to 36 hours Format: Pill or chewable tablet (patient choice)
Hims 3-in-1

Hims 3-in-1

3-in-1
SildenafilTadalafilOxytocin

Pill or chewable tablet (patient choice) · 30–60 minutes onset · Up to 36 hours

Onset30–60 minutes
DurationUp to 36 hours
FormatPill or chewable tablet (patient choice)
PriceVaries by plan
Visit Hims ↗

Our Verdict

Men whose ED has a relational or emotional component. Also ideal for men who prefer pill or chewable format flexibility, or who already use Hims for other services.

Pros & Cons

Pros
  • Unique oxytocin third ingredient — addresses emotional/relational dimension of intimacy
  • Only provider offering pill OR chewable tablet format choice
  • Large, established telehealth platform with broad US state availability
  • Strong customer service infrastructure
  • Dual PDE5 coverage (sildenafil + tadalafil) plus hormonal support
Cons
  • 30–60 minute onset — significantly slower than sublingual competitors
  • Oxytocin evidence base for ED specifically still developing
  • Pricing varies by plan — less transparent than per-dose pricing

What Makes Hims 3-in-1 Unique

Only combination formula with oxytocin — the bonding hormone — addressing the relational dimension of sexual arousal that PDE5 inhibitors and dopamine agonists alone don't reach.

The only combination ED formula with oxytocin — targeting the relational and emotional dimension of intimacy alongside physical function. The formula is prescribed by licensed clinicians through a fully online intake process and compounded at a licensed pharmacy — no in-person visit required.

Clinical Process & Access

Fully online intake through Hims platform. Licensed clinician review. Prescription fulfilled through Hims pharmacy network. Multiple plan tiers available; pricing discussed during consultation.

All medications dispensed require a valid prescription from a licensed clinician. Hims operates as a telehealth platform — you complete an intake form online, a clinician reviews your history, and if appropriate issues a prescription. The compounded medication is shipped to your door in discreet packaging.

Important: Always disclose your complete medication list and cardiovascular history during intake. PDE5 inhibitors are contraindicated with nitrates.

Ready to Try Hims 3-in-1?

Varies by plan · Online consultation included · Discreet shipping

Visit Hims ↗
← Compare All ED Formulas
Medical & Advertising Disclaimer This page is for informational and comparison purposes only and does not constitute medical advice. All medications require a prescription from a licensed clinician. ExploreTreatments/BestEdTreatment.com may receive compensation when you click affiliate links. Rankings are editorially independent.